Generating Genome-Scale Candidate Gene Lists for Pharmacogenomics
نویسندگان
چکیده
منابع مشابه
Pharmacogenomics: candidate gene identification, functional validation and mechanisms.
Pharmacogenetics is the study of the role of inheritance in variation in drug response phenotypes. Those phenotypes can range from life-threatening adverse drugs reactions at one end of the spectrum to equally serious lack of therapeutic efficacy at the other. Over the past half century, pharmacogenetics has--like all of medical genetics--evolved from a discipline with a focus on monogenetic tr...
متن کاملWhole genome sequencing in pharmacogenomics
Pharmacogenomics aims to shed light on the role of genes and genomic variants in clinical treatment response. Although, several drug-gene relationships are characterized to date, many challenges still remain toward the application of pharmacogenomics in the clinic; clinical guidelines for pharmacogenomic testing are still in their infancy, whereas the emerging high throughput genotyping technol...
متن کاملThe Utility of Corpora Comparison for Generating Delete Lists
Support for this work was provided by the Office of Naval Research (ONR) MURI N0014081186 as well as ONR Minerva – Dynamic Statistical Network Informatics N000141512797. Additional support was provided by the center for Computational Analysis of Social and Organizational Systems and the Institute for Software Research at Carnegie Mellon University. The views and conclusions contained in this do...
متن کاملGenerating Task-Pertinent sorted Error Lists for Speech Recognition
Automatic Speech recognition (ASR) is one of the most widely used components in spoken language processing applications. ASR errors are of varying importance with respect to the application, making error analysis keys to improving speech processing applications. Knowing the most serious errors for the applicative case is critical to build better systems. In the context of Automatic Speech Recog...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Pharmacology & Therapeutics
سال: 2009
ISSN: 0009-9236,1532-6535
DOI: 10.1038/clpt.2009.42